Welcome to the Ulijn Group website. The work in our group is focused on the development of minimalistic molecular materials and systems that are inspired by biology and have unique properties, such as adaptability, molecular recognition and programmability. These properties open up exciting new applications in wide ranging areas ranging from biomedicine to nanotechnology. [Group Members and Full Biography]
Nanoscientists Move into the New ASRC Building
After a decade of planning, the ASRC building has been completed. Today, the first researchers of the Nanoscience Initiative, under direction of Dr Rein Ulijn, have moved into the building. [Read more]
In this paper, we introduce a new approach to catalyst discovery. This is achieved by combining catalytic self-assembly with phage display. We demonstrate the discovery of catalysts for amide condensation and hydrolysis in water, an extremely challenging reaction with an estimated uncatalyzed half-life in the range of 300 years. While oligopeptides have proven their worth as building blocks for molecular self-assembly and as selective ligands to achieve molecular recognition, our work provides a step towards applying them in design of minimalistic enzyme mimics.