Welcome to the Ulijn Group website. The work in our group is focused on the development of minimalistic molecular materials and systems that are inspired by biology and have unique properties, such as adaptability, molecular recognition and programmability. These properties open up exciting new applications in wide ranging areas ranging from biomedicine to nanotechnology. [Group Members and Full Biography]
Nanoscientists Move into the New ASRC Building
After a decade of planning, the ASRC building has been completed. Today, the first researchers of the Nanoscience Initiative, under direction of Dr Rein Ulijn, have moved into the building. [Read more]
Controlling Cancer Cell Fate using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile
In Yousef' latest paper, in collaboration with the 3B's/University of Minho, we report on the biocatalytic self-assembly of a carbohydrate amphiphile. This system showed the ability for localised assembly triggered by the alkaline phosphatase produced by osteosarcoma cell line resulting in cell death. We show that this effect depends on the phosphatase concentration and is cell-selective. These results demonstrate that simple carbohydrate derivatives can be used in an anti-osteosarcoma strategy with limited impact on the surrounding healthy cells/tissues.