Publications by Year - 2010

R.J. Williams, R.J. Mart, R.V. Ulijn, Exploiting biocatalysis in peptide self-assembly, Peptide Science, 2010, 94, 107-117.

2009

A.M. Smith, R.J. Collins, R.V. Ulijn, E. Blanch, Raman Optical Activity of an achiral element in a chiral environment, Journal of Raman Spectroscopy, 2009, 40, 1093-1095.

Y. Li, B.G. Cousins, R.V. Ulijn, I.A. Kinloch, A study of the dynamic interaction of surfactants with graphite and carbon nanotubes using Fmoc-amino acids as a model system, Langmuir, 2009, 25, 11760-11767.

K. Thornton, A.M. Smith, C.L.R. Merry, R.V. Ulijn, Controlling stiffness in nanostructured hydrogels produced by enzymatic dephosphorylation, Biochemical Society Transactions, 2009, 37, 660-664.

C. Tang, A.M. Smith, R.F. Collins, R.V. Ulijn, A. Sainani, Fmoc-Diphenylalanine self-assembly mechanism induces apparent pKa shifts, Langmuir, 2009, 25, 9447-9453.

T.O. McDonald, A. Patrick, R. Williams, B.G. Cousins, R.V. Ulijn; Carpi & Smela, Eds., Biomedical Applications of Electractive Polymer Actuators, 2008, Wiley.

A.K. Das, A. Hirst, R.V. Ulijn, Evolving nanomaterials using enzyme-driven dynamic peptide libraries (eDPL), Faraday Discussions, 2009, 143, 293-303.

S.J. Todd, D.J. Scurr, J.E. Gough, M.R. Alexander, R.V. Ulijn, Enzyme-activated RGD ligands on functionalized PEG monolayers: surface analysis and cellular response, Langmuir, 2009, 25, 7533–7539.

V. Jayawarna, S.M. Richardson, A. Hirst, N.W. Hodson, A. Saiani, J.E. Gough, R.V. Ulijn, Introducing Chemical Functionality in Fmoc-Peptide Gels for Cell Culture, Acta Biomaterialia, 2009, 5, 934-943.

M. Zhou, A.M. Smith, A.K. Das, N.W. Hodson, R.F. Collins, R.V. Ulijn, J.E. Gough, Self-assembled peptide-based hydrogels as scaffolds for anchorage dependent cells, Biomaterials, 2009, 30, 2523-2530.

T.O. McDonald, H. Qu, B.R. Saunders, R.V. Ulijn, Branched Peptide Actuators for Enzyme Responsive Hydrogel Particles, Soft Matter, 2009, 5, 1728-1734.

B.G. Cousins, A.K. Das, R. Sharma, Y. Li, J.P. McNamara, I.H. Hillier, I.A. Kinloch, R.V. Ulijn, Enzymatically Activated Peptide-based Surfactants for Dispersing Carbon Nanotubes, Small, 2009, 5, 587-590.

R.J. Williams, A.M. Smith, R. Collins, N. Hodson, A.K. Das, R.V. Ulijn, Enzyme Assisted Self-Assembly under Thermodynamic Control, Nature Nanotechnology, 2009, 4, 19-24.

2008

D.M Kalaskar, J.E. Gough, R.V. Ulijn, W.W. Sampson, D.J. Scurr , F.J. Rutten, M.R. Alexander, C.L.R. Merry, S.J. Eichhorn, Controlling cell morphology on amino acid modified cellulose, Soft Matter, 2008, 4, 1059-1065.

L.S. Birchall, R.V. Ulijn, S.J. Webb, A Combined SPS-LCD Sensor for Screening Protease Activity, Chem. Commun., 2008, 2861-2863.

A.M. Smith, R.J. Williams, C. Tang, P. Coppo, R.F. Collins, M.L. Turner, A. Saiani, R.V. Ulijn, Fmoc-Diphenylalanine Self Assembles to a Hydrogel via a Novel Architecture Based on Pi-Pi Interlocked Beta-Sheets, Adv. Mater., 2008, 20, 37-41.

A.K. Das, R. Collins, R.V. Ulijn, Exploiting Enzymatic (Reversed) Hydrolysis in Directed Self-Assembly of Peptide Nanostructures, Small, 2008, 4, 279-287.

P.D. Thornton, R.J. Mart, S. Webb, R.V.Ulijn, Enzyme-Responsive Hydrogel Particles for the Controlled Release of Proteins: Designing Peptide Actuators to Match Payload, Soft Matter, 2008, 4, 821-827.

A.M. Smith, R.V. Ulijn, Designing Peptide Based Nanomaterials, Chem. Soc. Rev., 2008, 37, 664-675.

2007

A. Bahi, J.T. Jones, C.M. Carr, R.V. Ulijn, and J. Shao, Surface Characterization of Chemically Modified Wool, Textile Res. J. 2007, 77, 937-945.

R.E. Rawsterne, S.J. Todd, J.E. Gough, D. Farrer, F. Rutten, M.R. Alexander, R.V. Ulijn, Cell Spreading Correlates with Log P of Surface Tethered Amino Acids, Acta Biomater., 2007, 3, 715-721.

A. Laromaine, L. Koh, M. Murugesan, R.V. Ulijn, M.M. Stevens, Enzyme-Triggered Dispersion of Nanoparticle Assemblies, J. Am. Chem. Soc., 2007, 129, 4156-4157.

P.D. Thornton, R.J. Mart, R.V. Ulijn, Enzyme-Responsive Polymer Hydrogel Particles for Controlled Release,  Adv. Mater., 2007, 19, 1352-1256.

S.J. Todd, D. Farrar, J.E. Gough, R.V. Ulijn, Enzyme-Triggered Cell Attachment to Hydrogel Surfaces., Soft Matter, 2007, 3, 547-550.

V. Jayawarna, A.M. Smith, J.E. Gough, R.V. Ulijn, Three-dimensional cell culture of chondrocytes on modified di-phenylalanine scaffolds. Biochemical Society Transactions, 2007, 35, 535-537.

R.V. Ulijn, N. Bibi, V. Jayawarna, P.D. Thornton, S.J. Todd, R.J. Mart, A.M. Smith, J.E. Gough, Bioresponsive hydrogels, Materials Today, April 2007, 10, 40-48.

2006

P.D. Thornton, R.V. Ulijn, Enzyme-Triggered Collapse of PEG-based particles, Materials Research Society Proceedings, 2006, 945E, 0947-A02-06 (Electronic Only).

R.J. Mart, R.D. Osborne, M.M. Stevens, R.V. Ulijn, Peptide-Based Stimuli-Responsive Biomaterials. Soft Matter, 2, 822-835 (Inside Cover - right).

R.E. Rawsterne, J.E. Gough, F.J.M. Rutten, N.T. Pham, W.C.K. Poon, S.L. Flitsch, B. Maltman, M.R. Alexander, R.V. Ulijn Controlling Protein Retention on Enzyme Responsive Surfaces, Surf. Interf. Anal., 2006, 38, 1505-1511.

R.V. Ulijn. Enzyme responsive materials: a new class of smart biomaterials. J. Mat. Chem., 2006, 16, 2217-2225 (Front cover - right).

S. Toledano, R.J. Williams, V. Jayawarna, R.V. Ulijn. Enzyme triggered self-assembly of peptide hydrogels via reversed hydrolysis. J. Am. Chem. Soc., 2006, 128, 1070-1071.

M. Zourob, J.E. Gough, R.V. Ulijn. A micro-patterned hydrogel platform for chemical synthesis and biological analysis. Adv. Mater.,2006, 18, 655-659 (Front cover - right).

V. Jayawarna, M. Ali, T.A. Jowitt, A.F. Miller, A. Saiani, J.E. Gough, R.V. Ulijn, Nano-structured hydrogels for 3D cell culture through self-assembly of Fmoc-dipeptides. Adv. Mater., 2006, 18, 611-614.

2005

P. Thornton, G. McConnell, R.V. Ulijn, Enzyme responsive polymer hydrogel beads, Chem. Commun., 2005, 47, 5913-5915.

P.J.Halling, R.V. Ulijn, S.L. Flitsch, Understanding enzyme action on immobilised substrates, Curr. Opin. Biotechnol., 2005, 16, 1-8.

2004

R.V. Ulijn, P.J. Halling, Solid-to-Solid Synthesis: thermodynamic feasibility and energy efficiency, Green Chemistry 2004,6,488-496.

R.H.P. Doeze, B.A. Maltman, C.L. Egan, R.V. Ulijn, S.L. Flitsch. Profiling Primary Protease Specificity via Peptide Synthesis on Solid Support, Angew. Chem. Int. Ed. 2004, 43, 3138-3141.

A. Basso, R.V. Ulijn, S.L. Flitsch, G. Margetts, I. Brazendale, C. Ebert, L. De Martin, P. Linda, S. Verdelli, L. Gardossi. Introduction of permanently charged groups into PEGA resins leads to improved biotransformations on solid support 2004, Tetrahedron, 60(3), 589-594.

2003

C.E. Humphrey, N.J. Turner, M.A.M. Easson, S.L. Flitsch, R.V. Ulijn. Lipase catalysed kinetic resolution on solid-phase via a "capture and release" strategy: an unexpected reversal of selectivity. J. Am. Chem. Soc. 2003, 125, 13952-13953.

A.Basso, L. De Martin, C. Ebert, P. Linda, L. Gardossi, R.V. Ulijn, S.L. Flitsch, Organically modified xerogels as supports for solid-phase chemistry. 2003, Tet. Lett. 44, 6083-6085.

A.Y. Bosma, R.V. Ulijn, G. McConnell, J. Girkin, P.J. Halling, S.L.Flitsch 2003 Using two photon microscopy to quantify enzymatic reaction rates on polymer beads. Chem. Commun. 2003, 2790-2791.

A.Basso, L.Gardossi, R.V. Ulijn, S.L.Flitsch, G.Margetts, I. Brazendale, Improved biotransformations on charged PEGA supports. Chem. Commun. 2003, 1296-1297.

R.V. Ulijn, N. Bisek, S.L. Flitsch, P.J.Halling. Understanding protease catalysed peptide synthesis on solid support. Org. Biomolec. Chem. 2003, 1, 1277-1281.

R.V. Ulijn, I. Brazendale, G. Margetts, S.L. Flitsch, G. McConnell, J. Girkin, P.J. Halling, Two photon Microscopy to Spatially Resolve and Quantify Fluorophores in Single-Bead Chemistry. J. Combi. Chem. 2003, 5, 215-217.

R.V.Ulijn, N. Bisek, S.L. Flitsch. Enzymatic optical resolution via acylation-hydrolysis on a solid support. Org. Biomolec. Chem. 2003, 1, 621-622.

S.L. Flitsch, R.V. Ulijn, Sugars tied to the spot. Nature 2003, 421, 219-220.

R.V. Ulijn, L. De Martin, L. Gardossi, P.J. Halling, Biocatalysis with mainly undissolved solid substrates. Curr. Org. Chem., 2003, 7, 1333-1346.

L. Marchal, R.V. Ulijn, C.D. De Gooijer, G.T. Franke, J. Tramper. Monte Carlo simulation of the a-amylolysis of amylopectin potato starch. 2. a-amylolysis of amylopectin. Bioproc. Biosys. Eng., 2003, 26(2), 123-132.

2002

R.V. Ulijn, A.E.M. Janssen, B.D. Moore, P.J. Halling, S.M. Kelly, N.C.Price, Reversible acetonitrile-induced inactivation/activation of thermolysin. ChemBioChem, 2002, 3(11), 1112-1116.

R.V. Ulijn, B. Baragana, P.J. Halling, S.L. Flitsch Protease catalyzed peptide synthesis on solid support. J. Am. Chem. Soc. 2002, 124, 10988-10989.

R.V. Ulijn, B.D. Moore, A.E.M. Janssen, P.J. Halling A single aqueous equilibrium constant for peptide synthesis/hydrolysis. J. Chem. Soc. Perkin Trans. II, 2002, 5, 1024-1028.

R.V. Ulijn, L. De Martin, L. Gardossi, A.E.M. Janssen, B.D. Moore, P.J. Halling Solvent selection for solid to solid biocatalysis. Biotechnol. Bioeng. 2002, 80, 509-515.

R.V. Ulijn, L. De Martin, A.E.M. Janssen, B.D. Moore, P.J. Halling Enzymatic synthesis of beta lactam antibiotics via direct condensation. J. Biotechnol. 2002, 99, 215-222.

2001

R.V. Ulijn, A.E.M. Janssen, B.D. Moore, P.J. Halling Predicting when precipitation driven synthesis is feasible: application to biocatalysis. Chem. Eur. J., 2001, 7, 2089-2098.

2000

R.V. Ulijn, M. Erbeldinger, P.J. Halling Comparison of methods for thermolysin catalysed peptide synthesis including a novel more active catalyst. Biotechnol. Bioeng., 2000, 69, 633-638.

G. Bell, P.J. Halling, L. May, B.D. Moore, D. Robb, R.V. Ulijn, R.H. Valivety E.N. Vulfson, P.J. Halling and H.L. Holland, Eds. Methods in Biotechnology: Enzymes in non-aqueous solvents, 2000, Humana Press.

Patent Applications

Stevens, Molly M.; Ulijn, Rein; Laromaine, Sague Anna; Koh, Liling. Particles. PCT Int. Appl. (2007), 36pp.

Ulijn, Rein Vincent; Jayawarna, Vineetha; Smith, Andrew; Gough, Julie Elizabeth. Hydrogel compositions for cell culture. U.S. Pat. Appl. Publ. (2007), 24pp.

Ulijn, Rein Vincent; Toledano, Sophie. Method of preparing a hydrogel. PCT Int. Appl. (2007), 62pp.

Ulijn, Rein Vincent; Thornton, Paul David; Mart, Robert John. Protease-responsive PEGA-based hydrogel particle for pharmaceutical and affinity chromatography use. PCT Int. Appl. (2007), 84pp.

Flitsch, Sabine; Ulijn, Rein; Doeze, Ronnie Henricus Petrus. Profiling primary protease specificity by peptide synthesis on a solid support. PCT Int. Appl. (2005), 26pp.